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Epidemiology and statistics Test (Part 1)

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1) Hypemesis gravidarum occurs in what percentage of pregnancies?

2) Which of the following tests require the population to be of normal distribution

3) Which of the following studies is most appropriate to assess a prognosis of a disease?

4) The World Health Organisation (WHO) define maternal death as

5) What is the incidence rate of ovarian cancer per 100,000 females in the UK?

6) A 34 year old patient sustains a 3b perineal tear following delivery of her 3rd child. What is the UK incidence of OASIS (obstetric anal sphincter injury) in multiparous women?

7) A small study looks at medical records of deceased women to see how many smoked and how many were diagnosed with breast cancer. The results are below

8) Which of the following is a parametric test used to test correlation?

9) Regarding uterine cancer in the UK. What is the average age at diagnosis?

10) Regarding Venous Thomboembolism (VTE) in pregnancy which of the following statements is TRUE?

11) Following a single episode of reduced fetal movements what percentage of pregnancies will be uncomplicated?

12) Specificity is calculated by

13) What is the most common site of ectopic pregnancy implantation?

14) A study looked at 40,000 women at a maternity unit in an area with a population of 520,000. The number of identified VTE episodes was 60 with a standard deviation of 20. Using the figures what is the standard error of the mean (SEM)?

15) Which of the following is the least common cause of maternal mortality

16) A new test for Group B strep has been designed and the results are shown above. Which of the below is the Negative Predictive Value?

17) Which of the following studies is most appropriate to assess a diagnostic test?

18) What is the prevalence of antiphospholipid syndrome in patients with recurrent miscarriage?

19) Which of the following has been shown to increase ovarian cancer risk?

20) Regarding the table above which of the below formulas would you use to calculate the positive likelihood ratio?

21) Which of the following is known to increase the risk of endometrial cancer?

22)

A patient arrives on labour ward she is 37 weeks pregnant. Her last pregnancy ended with delivery via uncomplicated lower segment C‐Section 4 years ago. Contractions are 5 minutes apart and on examination the cervix is 5cm dilated. What is the risk of uterine rupture with
vaginal delivery?

23) A patient arrives on labour ward she is 37 weeks pregnant. Her last pregnancy ended with delivery via uncomplicated lower segment C‐Section 4 years ago. Contractions are 5 minutes apart and on examination and the cervix is 5cm dilated. She wants to know the risk to the baby of proceeding with vaginal delivery. What is the risk of the infant developing hypoxic ischaemic encephalopathy with VBAC?

24) A new test for Group B strep has been designed and the results are shown above. Which of the below represents the Specificity?

25) A new test for Group B strep has been designed and the results are shown above. Which of the below is the Sensitivity?

26) Regarding Pulmonary Embolism in Pregnancy which of the following statements is true?

27) Sensitivity is calculated by

28) A small study shows the lifetime incidence of breast cancer in smokers to be 20 in 100. In non smokers the incidence is 10 in 100. Which of the following represents the absolute risk of breast cancer in smokers?

29) Regarding uterine fibroids (leiomyoma) which of the following statements is TRUE regarding their prevalence?apart and on examination and the cervix is 5cm dilated. She wants to know the risk

30) What is the incidence of placenta accreta (including increta and percreta) in the UK?

31) A patient arrives on labour ward she is 37 weeks pregnant. Her last pregnancy ended with delivery via uncomplicated lower segment C‐Section 4 years ago. Contractions are 5 minutes apart and on examination and the cervix is 5cm dilated. She wants to know the risk to the baby of proceeding with vaginal delivery (VBAC). What is the additional risk the baby will have respiratory problems after VBAC compared to elective repeat C‐section (ERCS)?

32) What is the incidence of molar pregnancy in the UK?

33) Study Z gets funding to increase the population size from 1000 to 2000 patients. What effect is this likely to have on the results?

34) A new test for Group B strep has been designed and the results are shown above. Which of the 6below represents the Positive Likelihood ratio?

35) What is the incidence of choriocarcinoma in the UK?

36) A 26 year old patient sustains a 3b perineal tear following delivery of her 1st baby. What is the UK incidence of OASIS (obstetric anal sphincter injury) in primiparous women?

37) Which of the following studies is most appropriate to assess the efficacy of a new medication to reduce pain caused by endometriosis?

38) Regarding uterine fibroids (leiomyoma) which of the following statements is TRUE regarding their prevalence?

39)

A patient arrives on labour ward she is 38 weeks pregnant. Her last and only pregnancy ended with delivery via uncomplicated lower segment C‐Section 3 years ago. Contractions are 6 minutes apart and on examination and the cervix is 6cm dilated. She wants to know the
chances of a successful vaginal delivery if she proceeds with a vaginal delivery after c‐section(VBAC). What is the chance of successful delivery with VBAC?

40) A study looks at the average systolic blood pressure of patients in antenatal clinic. Out of 200 women the average SBP was 110mmHg and the standard error of the mean was 8mmHg. What is the 95% confidence interval

41) Which of the following statements regarding fibroids is FALSE?

42) Negative Predictive Value is

43) What is the incidence of obstetric cholestasis in England?

44) Positive Predictive Value is

45) Which of the following is NOT a recognised cause of hyperprolactinaemia?

46) The World Health Organisation define the maternal mortality ratio as

47) Which of the following factors as shown to decrease ovarian cancer risk?High Coffee consumption

48) A new test for Group B strep has been designed and the results are shown above. Which of the below represents the Negative Likelihood ratio?

49) WHO defines the perinatal mortality rate as

50) Which of the following reduces the risk of fibroids?

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