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molar pregnancy-early pregnancy care part 2

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1)

A 21-yr old woman attended the hospital at 6 wks of amenorrhea and a +ve home
pregnancy test. A likely miscarriage was diagnosed on USG and she opted for surgical
evacuation. Product of conception demonstrated partial H. mole.

2)

woman has had surgical management of miscarriage and a molar pregnancy has been
confirmed.
Which immunohistochemistry marker is useful for distinguishing between partial and complete
molar pregnancies?

3)

A woman has undergone surgical management of miscarriage and a partial molar pregnancy
has been confirmed. Referral to a specialist centre is advised.
Where are the three specialist referral centres in the United Kingdom?

4) What percentage of partial molar pregnancies consist of tetraploid or mosaic conceptions?

5)

A woman has attended the gynaecology clinic to discuss a diagnosis of a molar pregnancy.
What is the definitive method of diagnosis?

6)

The same 21-yr old woman re-attends hospital 15 weeks later with persistent vaginal
bleeding. Her serum HCG has risen to 6000 mIU/ml

7)

A woman has undergone surgical management of miscarriage and the histology confirms
Gestational Trophoblastic Disease (GTD). What is the expected incidence of GTD in the United
Kingdom?

8)

A 24-yr old multiparous woman is diagnosed with GTN 6 months following a partial mole
and has a single 6 cm metastasis in the liver

9)

. A 21-yr old primiparous woman who has had a previous molar pregnancy is now pregnant
one year later. Her pregnancy appears to be progressing well. How would u manage her
following delivery?

10)

Following appropriate treatment of complete and partial molar pregnancies, what
percentage of women need additional chemotherapy in each case, respectively?

11)

A woman has had an ultrasound scan and the possibility of a molar pregnancy with a coexisting twin has been raised by the sonographer.
The woman has been referred to a regional fetal medicine centre for further investigations.
What would be the most appropriate investigation?

12)

You are reviewing a 36-year-old woman who has undergone a surgical evacuation for a
molar pregnancy. Which one of the following forms part of the FIGO scoring system for
gestational trophoblastic disease (GTD)?

13)

A 35-year-old woman presents to the early pregnancy unit with moderate vaginal bleeding.
An ultrasound is performed, which reports a complete molar pregnancy.
What would be the genetic complement and parental origin of the complete molar pregnancy?

14)

A woman has been diagnosed with high-risk gestational trophoblastic neoplasia (GTN) and is
about to receive multiagent chemotherapy. What is the expected cure rate?

15)

A 43-yr old multiparous woman is diagnosed with gestational neoplastic disease 3 months
following a surgical termination. Her serum HCG is 10,000 mIU/ml. she has 2 small (1 cm)
metastases in the lung

16)

The general practitioner calls to ask about the immediate follow-up of a woman who had a
suction evacuation of a complete molar pregnancy. What is your advice?

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